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Going to a Cleveland Clinic location? You may not have symptoms in the beginning stages of the disease. Common causes include alcohol abuse, hepatitis and nonalcoholic fatty liver disease. Treatment depends on the cause of cirrhosis and how much damage exists. Liver transplantation may be an option if your liver is failing. Appointments What is cirrhosis of the liver? Cirrhosis is a late-stage liver disease in which healthy liver tissue is replaced with scar tissue and the liver is permanently damaged. Scar tissue keeps your liver from working properly. Many types of liver diseases and conditions injure healthy liver cells, causing cell death and inflammation.
This is followed by cell repair and finally tissue scarring as a result of the repair process. It also reduces the production of proteins and other substances made by the liver. Cirrhosis eventually keeps the liver from working properly. Late-stage cirrhosis is life-threatening. Scientists estimate that cirrhosis of the liver affects about one in adults in the U.
It affects about 1 in adults age 45 to 54, the age group most commonly affected by cirrhosis. Cirrhosis causes about 26, deaths each year in the U. However, most people who have liver cancer have cirrhosis. If you have cirrhosis, you have an increased risk of liver cancer.
If you have hepatitis B or hepatitis C, you have an increased risk of liver cancer because these diseases often lead to cirrhosis. Any cause of liver disease can lead to cirrhosis, which increases your chance of liver cancer. Even if you have hepatitis B or fatty liver disease without cirrhosis, you are at increased risk of liver cancer. Cirrhosis itself is not an inherited passed from parent to child disease. However, some of the diseases that can cause liver damage that lead to cirrhosis are inherited diseases. Generally no. If you have been told you have cirrhosis, you have a late-stage liver disease and the damage that is already Brown people having sex Cleveland Ohio is permanent.
There are many liver diseases and complications of liver diseases that can lead to cirrhosis. If your liver disease or complication is caught early and successfully managed, it may be possible to slow or stop the progression of disease. However, as cirrhosis continues, more scarring occurs and liver function continues to decline. Eventually, your failing liver may become a life-threatening condition. You and your medical team will discuss if you are a candidate for a liver transplant. If so, you will begin the process of being placed on a national liver transplant recipient list.
The symptoms of cirrhosis depend on the stage of your disease. In the beginning stages, you may not have any symptoms. If you do have symptoms, some are general and could easily be mistaken for symptoms of many other diseases and illnesses. As liver function gets worse, other more commonly recognized symptoms of cirrhosis appear including:. Yes, cirrhosis can be painful, especially as the disease worsens.
Most people with liver disease report abdominal pain. Pain in your liver itself can feel like a dull throbbing pain or a stabbing sensation in your right upper abdomen just under your ribs. General abdominal pain and discomfort can also be related to swelling from fluid retention and enlargement of your spleen and liver caused by cirrhosis. For instance, if you have non-alcoholic fatty liver disease and are obese, you may also have osteoarthritis and cirrhosis makes your bone and t pain worse.
Cirrhosis also causes an inflammatory state in your entire body. Changes from liver diseases that lead to cirrhosis are gradual. Liver cells are injured and if injury — from whatever cause — continues, liver cells start to die. There are many complications of cirrhosis of the liver.
Because cirrhosis develops over many years, some of these complications may be your first noticeable s and symptoms of the disease. Portal hypertension: This is the most common serious complication. Portal hypertension is an increase in the pressure in your portal vein the large blood vessel that carries blood from the digestive organs to the liver. This increase in pressure is caused by a blockage of blood flow through your liver as a result of cirrhosis. When blood flow through veins is partially blocked, veins in your esophagus, stomach or intestines can become enlarged a condition called varices.
As the pressure in these veins builds, the veins can bleed or even burst, causing severe internal bleeding. Hypersplenism: Hypersplenism is an overactive spleen. This condition causes quick and premature destruction of blood cells. Infections: Cirrhosis increases your risk of getting and fighting serious infections, such as bacterial peritonitis infection of the tissue that lines the inner wall of your abdomen.
Malnutrition: Your liver processes nutrients. A damaged liver makes this more difficult and le to weight loss and general weakness. Liver cancer: Most people who develop liver cancer have cirrhosis of the liver. Liver failure: Many diseases and conditions cause liver failure including cirrhosis of the liver. Your healthcare provider will first ask about your medical history and over-the-counter and prescription drug use.
They will also ask about any supplements or herbal products you may take. Your provider may suspect you have cirrhosis if you have a long history of alcohol abuse, injectable drug abuse or have had hepatitis B or C and have the symptoms listed in this article. To diagnosis cirrhosis, your provider will perform a physical exam and may order one or more of the following tests:. In addition, other blood work will include a complete blood count to look for s of infection and anemia caused by internal bleeding and a viral hepatitis test to check for hepatitis B or C.
If you have been diagnosed with cirrhosis of the liver, you are already beyond the early stages of liver disease. Having cirrhosis means your liver has scar tissue in it because it has been damaged. Liver specialists and researchers have developed many different scoring systems to predict outcome and to guide treatment for chronic liver disease.
Some specific liver diseases also have their own scoring systems. He or she may refer to you having either compensated cirrhosis or decompensated cirrhosis. Brown people having sex Cleveland Ohio lab work and imaging findings may not be abnormal. A liver biopsy may be the only way to confirm a diagnosis of cirrhosis. Median survival in patients with compensated cirrhosis is approximately nine to 12 years. Median is the middle point in set of s, so an equal of individuals survived less than 9 to 12 years as the of individuals who survived over this time range. Decompensated cirrhosis means your cirrhosis has worsened to the point that you have noticeable symptoms.
Your healthcare provider recognizes your condition based on your history, physical and lab findings. You have at least one complication, which includes jaundice, ascites, hepatic encephalopathy, hepatorenal syndrome, variceal bleeding or liver cancer. You are usually admitted to the hospital for care. Median survival in patients with decompensated cirrhosis is approximately two years. No, there is no cure for cirrhosis. The damage already done to your liver is permanent. However, depending on the underlying cause of your cirrhosis, there may be actions you can take to keep your cirrhosis from getting worse.
These actions include:. Although there is no cure for cirrhosis, treatments can delay or stop its progress and reduce complications. Portal hypertension: Portal hypertension is mainly the result of chronic end-stage liver disease.
Treatment consists of treating its many complications. Treatments of portal hypertension include:. Bacterial peritonitis: Antibiotics and infusion of a protein albumin will be prescribed. Typically patients are admitted to the hospital for treatment and monitoring. Following a diagnosis of bacterial peritonitis, an oral antibiotic will be prescribed for daily use to prevent recurrence of infection.
Liver cancer: Treatment depends on the stage of your cancer and other factors. One or more treatments may be tried. Options include surgery to remove part of your liver or your whole liver to be replaced with a new liver as part of a liver transplantation and nonsurgical tumor-destroying methods including ablationchemotherapytargeted therapy drugs zero in on cancer genes or tissueimmunotherapy and radiation bead therapy inject bead that give off radiation into the blood vessels that feed the tumor.
Kidney failure: Treatment may include medication, dialysis and kidney transplant, depending on the cause and extent of failure. Liver failure: Treatment depends on if you have acute or chronic failure.
For chronic liver failure, diet and lifestyle changes include stopping alcohol and medications that harm the liver; eating less red meat, cheese and eggs; losing weight; controlling high blood pressure and diabetes and cutting down on salt. Acute treatments for liver failure include intravenous fluids to maintain blood pressure, laxatives to help flush toxins from the body and blood glucose monitoring. If you have either acute or chronic liver failure, your liver specialist may recommend a liver transplant.
Liver transplants can come from a living or deceased donor. Only a portion of the donor liver needs to be transplanted. The liver is the only human organ capable of growing back. Many tests are required of both you the liver transplant recipient and the person donating a portion of their liver or the cadaver liver liver from a deceased person.
If your doctors determine that you need a liver transplant, you will be placed on a national liver transplant waiting list, which lists patients by blood type, body size and severity of end-stage liver disease. Damage already done to your liver is permanent.
But your liver is a large organ. If part of your liver is still working, you might be able to slow the progression of disease, depending on its cause. For instance, if your cirrhosis is caused by alcohol abuse, you need to stop drinking immediately.
If you are obese or have diabetes, you will need to lose weight and manage your blood sugar so you can lower the damage caused by fatty liver disease. Life expectancy depends on several factors including the cause and severity of your cirrhosis, your response to treatments, presence of cirrhosis complications, your age and any other existing general health problems.
Ask your liver specialist about your life expectancy since every person is unique, with unique overall health issues and specific liver health issues. If your cirrhosis is advanced, liver transplantation may be an option. You and your doctors will discuss if this is an option for you. -Turcotte-Pugh CTP score, also known simply as the Child-Pugh score, is a clinical score that tells your doctors how severe your liver disease is and forecasts your expected survival rate. The scoring system provides a score on the presence of five clinical measures the lab values of bilirubin, serum albumin and prothrombin time; presence of ascites and Brown people having sex Cleveland Ohio encephalopathy and the degree of severity of each of these measures.
The worse your liver function is, the higher your MELD score and the higher your position is on the transplant list. Depending on the stage of your cirrhosis, different healthcare providers may be involved in your care. Healthcare professionals likely to be part of your care team include:. Cirrhosis of the liver is a late-stage result of liver disease and its complications. Cirrhosis causes your liver to not function properly. Your liver plays a vital role in many of the processes and functions that keep you alive. Many of the causes and complications that lead to cirrhosis are treatable or manageable.
If you drink alcohol, stop. If you have nonalcoholic fatty liver disease, lose weight and control your metabolic risk factors. Take all medications for all your medical conditions as directed by your healthcare team. Get vaccinated for hepatitis A and B. You and your healthcare team will work together to closely manage your condition and put you on a wait list for a donor liver. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services.
Cirrhosis of the Liver Cirrhosis is a late-stage result of liver disease and its complications. How common is cirrhosis? Who gets cirrhosis, who is most at risk?Brown people having sex Cleveland Ohio
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